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Symptoms include shortness of breath during exercise and later during rest, as well as blue or grey skin from low oxygen levels. Also, experience of chest tightness or pain, fainting spells, pounding heartbeat or rapid pulse, swelling in the abdomen legs, and ankles, and fatigue are noticeable symptoms.
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Certain medical conditions may lead to the development of PAH. Lupus, Schistosomiasis, HIV, liver disease, Scleroderma, Pulmonary veno-occlusive disease, Congenital heart disease, and Genetic mutations are the major causes of PAH.
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Pulmonary hypertension is gradually progressive and can be fatal if left untreated. Though the treatment would not completely reverse the disease but there are therapies available to enhance the quality and lengthening of life, and make patients live better.
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Selection of Medicine is extremely important in the treatment of PAH. Pulmonary vasodilators are the main treatment. Nowadays newer molecules of these groups are successful in modifying disease courses and improving the quality of life of such patients. Calcium channel blockers, Balloon Atrial Septostomy (BAS), and diuretics are essential medical treatments. When a patient's blood oxygen levels are low, oxygen therapy is administered. If the PAH progresses despite optimum medical management Patient may require a Lung Transplant.
