When the kidneys have been damaged over a long period, and are slowly unable to filter blood. Over time, this damage tends to worsen if left unchecked and can lead to kidney failure.

One may be at risk if they have diabetes, high blood pressure, heart disease, or a family history of kidney failure.

Some common symptoms of advanced CKD include:

Increased or decreased urination

Loss of appetite

Muscle cramps

Nausea

Shortness of breath

Chest pain, and more

As these symptoms are not necessarily indicative of a failure in kidney function, it is advisable to always consult experts in the field.