Common Disorders and Symptoms
- Medical Specialities
- Allergy and Immunotherapy
- Common Disorders and Symptoms
-
Common Disorders and Symptoms
-
A. Immunodeficiencies- Immunodeficiency disorders disrupt immune function, making affected individuals more susceptible to infections. These conditions may be primary (inherited) or secondary (acquired).
-
Common Symptoms:
-
- Persistent, frequent, or severe infections that are difficult to treat
- Infections that are unusually prolonged
- Opportunistic infections (those that typically do not affect individuals with a healthy immune system)
- Unexplained recurrent fevers
- Chronic fatigue or lack of energy
- Digestive issues such as chronic diarrhoea, abdominal pain, nausea, or loss of appetite
- Persistent swollen lymph nodes
- Delayed growth and development in children
- Blood disorders, including anaemia or low platelet counts
- Inflammation and infections affecting internal organs
-
Specific Immunodeficiency Example: Common Variable Immunodeficiency (CVID)
-
CVID is typically diagnosed in adulthood, though symptoms may manifest in childhood. It is characterized by insufficient levels of immunoglobulins IgG, IgA, and IgM.
-
Common Symptoms:
-
- Recurrent infections, particularly affecting the respiratory tract (e.g., sinusitis, pneumonia, bronchitis, ear infections) and gastrointestinal system (e.g., abdominal pain, nausea, vomiting, diarrhea).
- Other possible manifestations include:
- Chronic rhinitis
- Swollen lymph nodes
- Unexplained weight loss
- Joint pain
-
CVID patients are also at increased risk for autoimmune disorders, certain malignancies, and chronic pulmonary diseases.
