Peritoneal Surface & Gynecology Cancer

Zydus Cancer Hospital / Peritoneal Surface & Gynecology Cancer

Paritoneal Cancer

What is Peritonaeal Cancer?

Peritoneal cancer is a rare cancer. It develops in a thin layer of tissue that lines the abdomen. It also covers the uterus, bladder, and rectum. Made of epithelial cells, this structure is called the peritoneum. Primary Peritoneal Cancer is more common in women than in men. Women at risk for ovarian cancer are also at increased risk for Peritoneal Cancer.

Symptoms of Peritonaeal Cancer:

  • Abdominal discomfort or pain from gas, indigestion, pressure, swelling, bloating, or cramps
  • Feeling of fullness, even after a light meal
  • Nausea or diarrhoea
  • Constipation
  • Frequent urination
  • Loss of appetite
  • Unexplained weight gain or loss
  • Abnormal vaginal bleeding
  • Rectal bleeding
  • Shortness of breath

Treatment of Peritoneal Cancer

HIPEC

HIPEC stands for Hyperthermic Intraperitoneal Chemotherapy. The aim of a HIPEC operation is to remove as much of the cancer as possible and then destroy any cancers cells that can’t be seen with the naked eye by putting hot chemotherapy inside the abdomen.

PIPAC

PIPAC stands for Pressurised Intra Peritoneal Aerosolised Chemotherapy. PIPAC is part of a clinical trial to see if it can shrink secondary cancers growing on the inside lining of the abdominal cavity (known as the peritoneum). These tumours are known as peritoneal metastases.

PIPAC is a type of chemotherapy given directly into a patient’s abdomen during an operation. After PIPAC is given, it stays inside the abdomen for 30 minutes, with the whole operation takes approximately two hours.

How PIPAC and HIPEC is Different?

Not all patients can undergo a HIPEC operation. One of the main reasons for this is some patients have too many tumours in their peritoneum. This is where PIPAC comes into play. The aim of the PIPAC operation is to get control of the cancer by shrinking the number and size of the tumours in the peritoneum. For some patients these tumours may shrink enough to mean that a HIPEC operation becomes possible in the future.

Gynaecology Cancer

What is Cervical Cancer?

Cervical Cancer is the second most common cancer among Indian women (As per Globocan 2018). Cervical Cancer is a preventable disease as it has a well-defined, long pre-malignant phase which can be detected by regular screening tests and follow ups. Unfortunately, most women in India are not aware about the screening.

What is Cervix?

The Cervix is the lower part of the womb also known as uterine cervix. The Cervix connects the body of the uterus to the vagina (birth canal). The part of the Cervix closest to the body of the uterus is called the endocervix. The part next to the vagina is the endocervix. The Cervix is about 2-3 cms in length.

Causes of Gynaecology Cancer?

  • Persistent infection of the cervix with Human Papillomavirus (HPV)
  • Having many sexual partners
  • Husband having multiple sexual partners
  • Having first sexual intercourse at a young age
  • Giving birth to many children
  • Smoking
  • Having other diseases which lower immunity such as HIV/AIDS, immunosuppressive drugs, transplant etc.

Preventions of Gynaecology Cancer:

  • Adopt safe sex practices (avoid multiple sexual partners).
  • Use of male condoms as barrier contraceptives to reduce the risk of HPV infection.
  • Timely treatment of reproductive tract infections.
  • There is evidence that circumcision for men may reduce the incidence of infection among sexual partners.
  • HPV vaccination
  • Pap smear test

Diagnosis of GI, Peritoneal & Gynaecology Cancer:

  • Colposcopy
  • Biopsy
  • PET Scan
  • Colonoscopy
  • Endoscopy
  • Blood Chemistry Analysis
  • Tumour Marker Tests
  • Loop electrosurgical excision procedure (LEEP)

Salient Features of GI, Peritoneal & Gynaecology Cancer:

  • Protocol and evidence-based treatment to get the best outcomes
  • Full-time dedicated specialists, so as to provide 24x7 services throughout the year
  • Subspecialty-based treatment of all cancers to get the best results
  • Well experienced & specially trained Surgeon of PIPAC, CRS & HIPEC surgery through Open and laparoscopic for all GI and Gynaecological malignanci