HIPEC stands for Hyperthermic Intraperitoneal Chemotherapy. In this procedure, a solution containing a chemotherapeautic agent in circulated in the abdominal/ peritoneal cavity and a high temperature for 30-90 mins.

HIPEC is done during surgery. During surgery, first all the tumor is removed which is called Cytoreductive Surgery (CRS) and then the hot solution containing the anti cancer drug (chemotherapy drug) is circulated in the abdominal cavity. By this process 1-2mm sized tumors can be destroyed. Microscopic tumor is also destroyed.

HIPEC is a single procedure done during surgery. Only 1 session is done at a time. Some patients can undergo a second HIPEC is the cancer comes back.


PIPAC is pressurized intraperitoneal aerosol chemotherapy. It is a new method of giving chemotherapy to patients with advanced abdominal cancer in which chemotherapy is given directly into the abdominal cavity. Routinely, chemotherapy (cancer directed therapy) is administered intravenously (through the veins) as a drip. Intra-peritoneal chemotherapy is given directly into the abdominal cavity in patients who have cancer spread to the peritoneum that is the lining of the abdominal cavity and its organs.

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